Southwest Oklahoma Vacations from $280

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Southwest Oklahoma Vacation

Book a Southwest Oklahoma vacation package and enjoy all the places your adventurous soul takes you. This vibrant destination has plenty to offer, including its adventure sports, watersports, walking trails, and so much more. With so much to do and see on a trip to Southwest Oklahoma, it can be hard to know where to start. Kick off your journey in Lawton at Comanche Nation Casino and Apache Casino Hotel — two popular attractions here. Another top city worth adding to your itinerary is Elk City. Be sure not to miss Elk City Golf and Country Club and Ackley Park. From the moment you book your Southwest Oklahoma vacation to when you get back home, Expedia will be with you every step of the way.

The Latest Southwest Oklahoma vacation packages

Price found within the past 48 hours. Click for updated prices.
La Quinta Inn & Suites by Wyndham Midwest City - Tinker AFB
Courtyard by Marriott Oklahoma City Downtown
Radisson Hotel Oklahoma City Airport
The Skirvin Hilton Oklahoma City
OYO Hotel Oklahoma City South I-35 and SE 29th
Don't see what you're looking for?
See all available trips from Columbus to Southwest Oklahoma
View all trips

Discover the most popular places to visit in Southwest Oklahoma

Southwest Oklahoma Hotel Deals

Apache Casino Hotel

Apache Casino Hotel

3.5 out of 5
2315 E. Gore Blvd., Lawton, OK
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $115 total per night from Aug 10 to Aug 11
$115 total
Aug 10 - Aug 11
Total includes taxes and fees
8.8/10 Excellent! (1,009 reviews)
"I will use Apache again"

Reviewed on Aug 4, 2025

Apache Casino Hotel
MySuites Lawton

MySuites Lawton

3 out of 5
3 Se Interstate Dr, Lawton, OK
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $83 total per night from Aug 11 to Aug 12
$83 total
Aug 11 - Aug 12
Total includes taxes and fees
8.8/10 Excellent! (1,320 reviews)
"This hotel was very clean and well maintained. The staff was very friendly and every time we've seen any of them workers that's exactly what they were doing working!"

Reviewed on Aug 1, 2025

MySuites Lawton
SureStay Plus by Best Western Lawton

SureStay Plus by Best Western Lawton

2.5 out of 5
1125 E Gore Boulevard, Lawton, OK
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $87 total per night from Aug 12 to Aug 13
$87 total
Aug 12 - Aug 13
Total includes taxes and fees
7.4/10 Good! (1,000 reviews)
"Really close to the casino"

Reviewed on Jul 28, 2025

SureStay Plus by Best Western Lawton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.